65 research outputs found

    Políticas identitarias de los cánones literarios argentino-brasileño: ¿una forma de exclusión cultural?

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    Luego de dos años de investigación, y con un subsidio del programa Redes Internacionales VII de la Secretaría de Políticas Universitarias del Ministerio de Educación de Argentina, hemos logrado un enriquecimiento de los estudios literarios sobre el canon, a través de la pesquisa y discusión del a temática propuesta entre los tres grupos de investigación participantes. Asimismo, se ha conseguido difundir y capitalizar en la tarea docente los resultados de la investigación, a través de seminarios de posgrado en Argentina y Brasil. Y finalmente, a través de la publicación de un libro conjunto, Nuevas lecturas sobre marginalidad, canon y poder en el discurso literario (BuenosAires: Ediciones Universidad del Salvador, 2015), y de la participación de los investigadores en reuniones científicas, se ha conseguido una eficaz difusión de los resultados obtenidos. En el curso de la investigación, se han descubierto varios derroteros que podrán identificarse y transitarse a través de los distintos abordajes que componen este volumen, pero principalmente se destacan: cómo el relieve de algunas temáticas, la visibilización de zonas fronterizas, espaciales y lingüísticas, y la emergencia o reelaboración de ciertas estéticas y enfoques han determinado que los autores o sus obras hayan sido confinados a posiciones de marginalidad. Desde luego, la tarea conjunta realizada ha significado la puesta en marcha de muchos mecanismos (administrativos y académicos) que han consolidado, además, las relaciones entre las tres instituciones participantes: la Universidad del Salvador (USAL), la Universidad Nacional de Lanús (UNLa) y la Universidad Estadual Paulista de Sâo Paulo (UNESP).After a two years’ research, subsidized by “Redes Internacionales VII” Program from the Ministry of Education’s Secretary of University Policies, our literary studies of the canon has been improved by means of investigation and discussion of the proposed topics that the three research groups involved have taken part of. Additionally, we succeeded in spreading the research’s outcome in postgraduate seminaries in Argentina and Brazil, which let us capitalize our findings in our teaching practice. In the course of the investigation, it has been discovered several directions that can be identified and transited through the different approaches in this volume, but mainly include: how the relief of some issues, the visibility of border, spatial and linguistic areas, and emergency or reprocessing of certain aesthetic and approaches, have determined that the authors or their works have been confined to marginal positions. Needless to say, the joint task has set in motion many administrative and academic mechanisms that have been strengthened since then, as well as the relationship between the three participating institutions: Universidad del Salvador (USAL), Universidad Nacional de Lanús (UNLa), and Universidad Estadual Paulista do Sâo Paulo (UNESP)

    The nature of services inflation in Brazil: 1999-2014

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    sem informaçãoEste artigo tem como objetivo analisar a dinâmica da inflação de serviços no Brasil. Para isso, procurou-se identificar os elementos constitutivos do Índice Nacional de Preços ao Consumidor Amplo passíveis de serem classificados como serviços desde 1999 e271199231sem informaçãosem informaçãosem informaçã

    Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

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    Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

    The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

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    Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase&nbsp;1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation&nbsp;disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age&nbsp; 6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score&nbsp; 652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc&nbsp;= 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N&nbsp;= 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in&nbsp;Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in&nbsp;Asia&nbsp;and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701

    Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

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    Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

    La enseñanza de español a brasileños : el lugar de la cultura

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    Se analiza si la cultura, especialmente la literatura, son importantes en el proceso de enseñanza de español como lengua extranjera. Se estudia este proceso en estudiantes para profesores de español lusohablantes.ES
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